circRNA basic information
circBase ID: -
Name: hsa_circ_STK39
Synonym: circSTK39
Host Gene: hsa-miR-125a-5p
 
 
 
Disease basic information
DO ID:
0070353
DO name: cataract
Disease details: age-related cataract
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: SRA01/04
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: ERCC6
Associated microRNA: hsa-miR-125a-5p
Biological function: -
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
1
Description:

The increased expression of circSTK39 ameliorated H(2)O(2)-induced SRA01/04 cell injury through the miR-125a-5p/ERCC6 pathway.

Other information
Title:

Ectopic circSTK39 Expression Ameliorates Hydrogen Peroxide-Induced Human Lens Epithelial Cell Apoptosis and Oxidative Stress through the miR-125a-5p/ERCC6 Pathway.

Journal: Curr Eye Res
Published: 2022/11/3
PubMed ID: 36322706