circRNA basic information
circBase ID: -
Name: hsa_circ_CYP51A1
Synonym: circCYP51A1
Host Gene: hsa-miR-490-3p
 
 
 
Disease basic information
DO ID:
 3347
DO name: osteosarcoma
Disease details: osteosarcoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: U2OS, MG63
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: KLF12
Associated microRNA: hsa-miR-490-3p
Biological function: cell proliferation, migration, invasion and glycolysis
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 3
Description:

CircCYP51A1 mediated cell proliferation, migration, invasion and glycolysis by regulating miR-490-3p/KLF12 axis in OS cells under hypoxia condition.
Other information
Title:

Silencing of circCYP51A1 represses cell progression and glycolysis by regulating miR-490-3p/KLF12 axis in osteosarcoma under hypoxia.

Journal: J Bone Oncol
Published: 2022/10/25
PubMed ID: 36276300