circRNA basic information
circBase ID: hsa_circ_0010220
Name: hsa_circ_ARHGEF10L
Synonym: circ_0010220
Host Gene: hsa-miR-574-3p
 
 
 
Disease basic information
DO ID:
 3347
DO name: osteosarcoma
Disease details: osteosarcoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: U2OS
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: IL-6
Associated microRNA: hsa-miR-574-3p
Biological function: resistance to DOX
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 3
Description:

Hsa_circ_0010220 encouraged OS resistance to DOX by miR-574-3p/IL-6 axis regulation, suggesting its potency as a promising biomarker for treating OS.
Other information
Title:

Has_circ_0010220 regulates the miR-574-3p/IL-6 axis to increase doxorubicin resistance in osteosarcoma.

Journal: Hum Exp Toxicol
Published: 2022/10/18
PubMed ID: 36250452