circRNA basic information
circBase ID: hsa_circ_0008365
Name: -
Synonym: circ_0008365
Host Gene: hsa-miR-338-3p
 
 
 
Disease basic information
DO ID:
 8398
DO name: osteoarthritis
Disease details: osteoarthritis
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: CHON-001
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: SOX9
Associated microRNA: hsa-miR-338-3p
Biological function: -
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 2
Description:

Circ_0008365 alleviates IL-1beta-induced CHON-001 cell damage through the miR-338-3p/SOX9 axis, which suggested that circ_0008365 might be a new therapeutic target for OA.
Other information
Title:

Circular RNA circ_0008365 regulates SOX9 by targeting miR-338-3p to inhibit IL-1beta-induced chondrocyte apoptosis and extracellular matrix degradation.

Journal: J Orthop Surg Res
Published: 2022/10/15
PubMed ID: 36242088