circRNA basic information
circBase ID: hsa_circ_0022383
Name: -
Synonym: Circ_0022383
Host Gene: hsa-miR-3619-5p
 
 
 
Disease basic information
DO ID:
 8398
DO name: osteoarthritis
Disease details: osteoarthritis
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: SIRT1
Associated microRNA: hsa-miR-3619-5p
Biological function: apoptosis, inflammation and ECM degeneration
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 1
Description:

Circ_0022383 protected chondrocytes from IL-1beta-induced apoptosis, inflammation and ECM degeneration by miR-3619-5p/SIRT1 axis.
Other information
Title:

Circ_0022383 alleviates IL-1beta-induced apoptosis, inflammation and extracellular matrix degeneration in osteoarthritis cell model by miR-3619-5p/SIRT1 axis.

Journal: Int Immunopharmacol
Published: 2022/10/5
PubMed ID: 36194985