circRNA basic information
circBase ID: hsa_circ_0007478
Name: hsa_circ_TM7SF3
Synonym: circ_0007478
Host Gene: hsa-miR-765
 
 
 
Disease basic information
DO ID:
 1936
DO name: atherosclerosis
Disease details: atherosclerotic plaque
Species: human
Species details: human
Sample type: cell line
Sample type details: THP-1
circRNA-disease information
Detected method:
M
Detected method confidence Low
Expression pattern:
UP
Associated gene: EFNA3
Associated microRNA: hsa-miR-765
Biological function: lipid metabolism
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 2
Description:

hsa_circ_0007478/miR-765/EFNA3 axis could also be involved in the inhibition of the lipid metabolism and foam cells formation in ox-LDL-macrophages.
Other information
Title:

Hsa_circ_0007478 aggravates NLRP3 inflammasome activation and lipid metabolism imbalance in ox-LDL-stimulated macrophage via miR-765/EFNA3 axis.

Journal: Chem Biol Interact
Published: 2022/10/4
PubMed ID: 36191606