circRNA basic information
circBase ID: hsa_circ_0005015
Name: hsa_circ_HAS2
Synonym: -
Host Gene: hsa-miR-519d-3p
 
 
 
Disease basic information
DO ID:
 8947
DO name: diabetic retinopathy
Disease details: diabetic retinopathy
Species: human
Species details: human
Sample type: tissue
Sample type details: -
circRNA-disease information
Detected method:
Q
M
Detected method confidence High
Expression pattern:
UP
Associated gene: MMP-2, XIAP, and STAT3
Associated microRNA: hsa-miR-519d-3p
Biological function: facilitated retinal endothelial angiogenic function via regulating endothelial cell proliferation, migration, and tube formation
Molecular mechanism: acted as hsa-miR-519d-3p sponge to inhibit hsa-miR-519d-3p activity, leading to increased MMP-2, XIAP, and STAT3 expression
Survival: -
Supported No.:
 1
Description:

CircRNAs are involved in DR pathogenesis, and thus serve as potential biomarkers of DR diagnosis.
Other information
Title:

Identification and Characterization of Circular RNAs as a New Class of Putative Biomarkers in Diabetes Retinopathy.

Journal: Invest Ophthalmol Vis Sci
Published: 2017/12/31
PubMed ID: 29288268