circRNA basic information
circBase ID: -
Name: hsa_circ_CEA
Synonym: Circ_CEA
Host Gene: -
 
 
 
Disease basic information
DO ID:
 10534
DO name: stomach cancer
Disease details: gastric cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: AGS, MKN28, BGC-823, MKN45, SGC-7901
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: -
Biological function: apoptosis
Molecular mechanism: -
Survival: -
Supported No.:
 1
Description:

circ_CEA protects GC cells from stress-induced apoptosis, via acting as a protein scaffold and interacting with p53 and CDK1 proteins.
Other information
Title:

Circ_CEA promotes the interaction between the p53 and cyclin-dependent kinases 1 as a scaffold to inhibit the apoptosis of gastric cancer.

Journal: Cell Death Dis
Published: 2022/9/28
PubMed ID: 36167685