circRNA basic information
circBase ID: -
Name: hsa_circ_MERTK
Synonym: CircMERTK
Host Gene: hsa-miR-125a-3p
 
 
 
Disease basic information
DO ID:
9256
DO name: colorectal cancer
Disease details: colorectal cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: THP-1
circRNA-disease information
Detected method:
S
Detected method confidence Low
Expression pattern:
UP
Associated gene: IL-10
Associated microRNA: hsa-miR-125a-3p
Biological function: immunosuppressive
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
1
Description:

TAM-like cell could exert immunosuppressive activity via circMERTK/miR-125a-3p/IL-10 axi.

Other information
Title:

CircMERTK modulates the suppressive capacity of tumor-associated macrophage via targeting IL-10 in colorectal cancer.

Journal: Hum Cell
Published: 2022/9/28
PubMed ID: 36163585