circRNA basic information
circBase ID: -
Name: -
Synonym: circRNA_100782
Host Gene: hsa-miR-124
 
 
 
Disease basic information
DO ID:
 3498
DO name: pancreatic ductal adenocarcinoma
Disease details: pancreatic ductal adenocarcinoma
Species: human
Species details: human
Sample type: cell line, PDX
Sample type details: PDAC cell lines (BxPC3, HPDE), HEK293T, BxPC3
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: interleukin-6 receptor (IL6R) and signal transducer and activator of transcription 3 (STAT3)
Associated microRNA: hsa-miR-124
Biological function: promoted proliferation
Molecular mechanism: acting as hsa-miR-124 sponge through the IL6-STAT3 pathway
Survival: -
Supported No.:
 1
Description:

these results suggest that circRNA_100782 regulates BxPC3 cell proliferation by acting as miR-124 sponge through the IL6-STAT3 pathway.
Other information
Title:

CircRNA_100782 regulates pancreatic carcinoma proliferation through the IL6-STAT3 pathway.

Journal: Onco Targets Ther
Published: 2017/12/20
PubMed ID: 29255366