circRNA basic information
circBase ID: hsa_circ_0003215
Name: -
Synonym: circ_0003215
Host Gene: hsa-miR-663b
 
 
 
Disease basic information
DO ID:
 9256
DO name: colorectal cancer
Disease details: colorectal cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: SW620, HCT116, SW480, DLD-1, LOVO, HT29
circRNA-disease information
Detected method:
Q
S
M
Detected method confidence High
Expression pattern:
DS
Associated gene: DLG4
Associated microRNA: hsa-miR-663b
Biological function: metabolic glucose reprogramming
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 1
Description:

m6A-modified circ_0003215 as a novel regulator of metabolic glucose reprogramming that inhibited the PPP and the malignant phenotype of CRC via the miR-663b/DLG4/G6PD axis.
Other information
Title:

N6-methyladenosine modification of circ_0003215 suppresses the pentose phosphate pathway and malignancy of colorectal cancer through the miR-663b/DLG4/G6PD axis.

Journal: Cell Death Dis
Published: 2022/9/21
PubMed ID: 36127319