circRNA basic information
circBase ID: hsa_circ_0050486
Name: -
Synonym: CircRNA_0050486
Host Gene: hsa-miR-1270
 
 
 
Disease basic information
DO ID:
1936
DO name: atherosclerosis
Disease details: atherosclerosis
Species: human
Species details: human
Sample type: cell line
Sample type details: THP-1
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-1270
Biological function: inflammation and apoptosis
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
1
Description:

circ_0050486 knockdown inhibited inflammation and apoptosis by targeting miR-1270 in oxLDL-induced THP-1 macrophages.

Other information
Title:

CircRNA_0050486 promotes cell apoptosis and inflammation by targeting miR-1270 in atherosclerosis.

Journal: Ann Transl Med
Published: 2022/9/17
PubMed ID: 36111016