circRNA basic information
circBase ID: -
Name: hsa_circ_ZNF609
Synonym: circ-ZNF609
Host Gene: -
 
 
 
Disease basic information
DO ID:
 3021
DO name: acute kidney failure
Disease details: acute kidney injury
Species: human
Species details: human
Sample type: tissue
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: -
Biological function: apoptosis
Molecular mechanism: AKT/mTOR-dependent mechanism
Survival: -
Supported No.:
 1
Description:

highly expressed circ-ZNF609-encoded ZNF609-250aa induces cell apoptosis and AKI by impairing the autophagy flux via an AKT/mTOR-dependent mechanism.
Other information
Title:

A protein encoded by circular ZNF609 RNA induces acute kidney injury by activating the AKT/mTOR-autophagy pathway.

Journal: Mol Ther
Published: 2022/9/17
PubMed ID: 36110046