circRNA basic information
circBase ID: -
Name: hsa_circ_ZFR
Synonym: CircZFR
Host Gene: hsa-miR-147a
 
 
 
Disease basic information
DO ID:
 9256
DO name: colorectal cancer
Disease details: colorectal cancer
Species: human
Species details: human
Sample type: cell line
Sample type details: Caco-2, HCT8, LoVo, HCT116, SW480
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: CACUL1
Associated microRNA: hsa-miR-147a
Biological function: apoptosis
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 2
Description:

Knockdown of the expression of circZFR upregulated miR-147a expression and reduced CACUL1 expression levels, thereby inhibiting the proliferation of CC cells and inducing cell cycle arrest and apoptosis.
Other information
Title:

Circular RNA ZFR promotes cell cycle arrest and apoptosis of colorectal cancer cells via the miR-147a/CACUL1 axis.

Journal: J Gastrointest Oncol
Published: 2022/9/13
PubMed ID: 36092343