circRNA basic information
circBase ID: -
Name: hsa_circ_LMTK2
Synonym: CircLMTK2
Host Gene: hsa-miR-485-5p
 
 
 
Disease basic information
DO ID:
1793
DO name: pancreatic cancer
Disease details: pancreatic cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: MIA-PaCa-2, PANC-1, BxPC-3, SW 1990
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: PAK1
Associated microRNA: hsa-miR-485-5p
Biological function: -
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
1
Description:

circLMTK2 knockdown attenuated GEM-resistant PC cells by regulating PAK1 via miR-485-5p.

Other information
Title:

CircLMTK2 Silencing Attenuates Gemcitabine Resistance in Pancreatic Cancer by Sponging miR-485-5p and to Target PAK1.

Journal: J Oncol
Published: 2022/9/6
PubMed ID: 36059806