circRNA basic information
circBase ID: -
Name: hsa_circ_FIRRE
Synonym: circFIRRE
Host Gene: hsa-miR-486-3p, hsa-miR-1225-5p
 
 
 
Disease basic information
DO ID:
3347
DO name: osteosarcoma
Disease details: osteosarcoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: -
circRNA-disease information
Detected method:
Q
S
Detected method confidence High
Expression pattern:
UP
Associated gene: LUZP1
Associated microRNA: hsa-miR-486-3p, hsa-miR-1225-5p
Biological function: -
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
1
Description:

upregulated circFIRRE was induced by transcription factor YY1, and partially boosted the mRNA and protein level of LUZP1 by sponging miR-486-3p and miR-1225-5p.

Other information
Title:

Circular RNA circFIRRE drives osteosarcoma progression and metastasis through tumorigenic-angiogenic coupling.

Journal: Mol Cancer
Published: 2022/8/20
PubMed ID: 35986280