circRNA basic information
circBase ID: -
Name: hsa_circ_LDLRAD3
Synonym: circ-LDLRAD3
Host Gene: hsa-miR-588
 
 
 
Disease basic information
DO ID:
 10534
DO name: stomach cancer
Disease details: gastric cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: NCI-N87, HGC-27, AGS
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: SOX5
Associated microRNA: hsa-miR-588
Biological function: DDP resistance
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 1
Description:

circ-LDLRAD3 knockdown reduced DDP resistance and blocked the malignant development of DDP-resistant GC by modulating the miR-588/SOX5 pathway.
Other information
Title:

circ-LDLRAD3 Knockdown Reduces Cisplatin Chemoresistance and Inhibits the Development of Gastric Cancer with Cisplatin Resistance through miR-588 Enrichment-Mediated SOX5 Inhibition.

Journal: Gut Liver
Published: 2022/8/18
PubMed ID: 35975639