circRNA basic information
circBase ID: hsa_circ_0001564
Name: hsa_circ_CANX
Synonym: -
Host Gene: hsa-miR-29c-3p
 
 
 
Disease basic information
DO ID:
 3347
DO name: osteosarcoma
Disease details: osteosarcoma
Species: human
Species details: human
Sample type: cell line
Sample type details: human osteosarcoma cell lines (U2OS, Saos-2, HOS, MG-63), normal human osteoplastic cell line (NHOst, HEK-293)
circRNA-disease information
Detected method:
M
Detected method confidence Low
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-29c-3p
Biological function: promoting cell proliferation and inhibiting cell apoptosis
Molecular mechanism: hsa_circ_0001564 acts as hsa-miR-29c-3p sponge to mediate the tumorigenicity
Survival: -
Supported No.:
 1
Description:

Our study discovers that hsa_circ_0001564 acts as miR-29c-3p sponge to mediate the tumorigenicity, which could act as a potential biomarker for the osteosarcoma and provide a novel insight for competing endogenous RNAs (ceRNAs) mechanism in osteosarcoma.
Other information
Title:

Circular RNA hsa_circ_0001564 regulates osteosarcoma proliferation and apoptosis by acting miRNA sponge.

Journal: Biochem Biophys Res Commun
Published: 2017/12/13
PubMed ID: 29229385