circRNA basic information
circBase ID: hsa_circ_0004585
Name: -
Synonym: circ_0004585
Host Gene: hsa-miR-874-3p
 
 
 
Disease basic information
DO ID:
 9256
DO name: colorectal cancer
Disease details: colorectal cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: HCT116, HCT8
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: CCND1
Associated microRNA: hsa-miR-874-3p
Biological function: -
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 3
Description:

Circ_0004585 promotes the development of CRC and increases 5-FU resistance in CRC through the miR-874-3p/CCND1 axis.
Other information
Title:

Knockdown of circ_0004585 enhances the chemosensitivity of colorectal cancer cells to 5-fluorouracil via the miR-874-3p/CCND1 axis.

Journal: Histol Histopathol
Published: 2022/7/29
PubMed ID: 35900059