circRNA basic information
circBase ID: -
Name: hsa_circ_PABPC1
Synonym: circPABPC1
Host Gene: hsa-miR-1292
 
 
 
Disease basic information
DO ID:
9256
DO name: colorectal cancer
Disease details: colorectal cancer
Species: human
Species details: human
Sample type: tissue
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-1292
Biological function: metastasis
Molecular mechanism: -
Survival: -
Supported No.:
1
Description:

exosomal circPABPC1 is an essential regulator in CRC liver metastasis progression by promoting HMGA2 and BMP4/ADAM19 expression.

Other information
Title:

Exosomal circPABPC1 promotes colorectal cancer liver metastases by regulating HMGA2 in the nucleus and BMP4/ADAM19 in the cytoplasm.

Journal: Cell Death Discov
Published: 2022/7/24
PubMed ID: 35871166