circRNA basic information
circBase ID: -
Name: hsa_circ_FAT1
Synonym: CircFAT1
Host Gene: hsa-miR-7
 
 
 
Disease basic information
DO ID:
 3910
DO name: lung adenocarcinoma
Disease details: lung adenocarcinoma
Species: human
Species details: human
Sample type: cell line
Sample type details: A549, PC9
circRNA-disease information
Detected method:
S
Detected method confidence Low
Expression pattern:
UP
Associated gene: IRS2
Associated microRNA: hsa-miR-7
Biological function: -
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 1
Description:

circFAT1 promote tumorigenesis in LUAD through sequestering miR-7, consequently upregulating IRS2-ERK1/2-mediated CCND1 expression.
Other information
Title:

CircFAT1 Promotes Lung Adenocarcinoma Progression by Sequestering miR-7 from Repressing IRS2-ERK-mediated CCND1 Expression.

Journal: Int J Biol Sci
Published: 2022/7/19
PubMed ID: 35844799