circRNA basic information
circBase ID: hsa_circ_0041732
Name: -
Synonym: circ_0041732
Host Gene: hsa-miR-541-3p
 
 
 
Disease basic information
DO ID:
 1612
DO name: breast cancer
Disease details: breast cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: KDM4A
Associated microRNA: hsa-miR-541-3p
Biological function: cell proliferation, cell cycle, and cell apoptosis
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 2
Description:

E2F4-mediated circ_0041732 upregulation resulted in the activation of NFkappaB and Hedgehog pathways via sponging miR-541-3p and enhancing expression levels of c, thus affecting breast cancer cell proliferation, cell cycle, and cell apoptosis.
Other information
Title:

circ_0041732 Promotes Breast Cancer Progression.

Journal: Mol Cancer Res
Published: 2022/7/16
PubMed ID: 35838496