circRNA basic information
circBase ID: -
Name: hsa_circ_LDLR
Synonym: circLDLR
Host Gene: hsa-miR-30a-3p
 
 
 
Disease basic information
DO ID:
 9256
DO name: colorectal cancer
Disease details: colorectal cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: HCT116, HT29, RKO, SW620, HCT8, LoVo, SW480, Caco-2
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: SOAT1
Associated microRNA: hsa-miR-30a-3p
Biological function: tumorigenesis and metastasis
Molecular mechanism: miRNA sponge
Survival: poor
Supported No.:
 1
Description:

circLDLR participates in CRC tumorigenesis and metastasis via the miR-30a-3p/SOAT1 axis.
Other information
Title:

Circular RNA circLDLR facilitates cancer progression by altering the miR-30a-3p/SOAT1 axis in colorectal cancer.

Journal: Cell Death Discov
Published: 2022/7/14
PubMed ID: 35821230