circRNA basic information
circBase ID: -
Name: hsa_circ_FBXL4
Synonym: circFBXL4
Host Gene: hsa-miR-146a-5p
 
 
 
Disease basic information
DO ID:
 10534
DO name: stomach cancer
Disease details: gastric cancer
Species: human
Species details: human
Sample type: cell line
Sample type details: GES-1, AGS, BGC-823, MGC-803, SGC-7901, HEK293
circRNA-disease information
Detected method:
Q
M
Detected method confidence High
Expression pattern:
DS
Associated gene: STAT1
Associated microRNA: hsa-miR-146a-5p
Biological function: lymphatic metastasis
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 1
Description:

LSECtin might be involved in the lymphatic metastasis of GC by upregulating the expression of FN1 and CHD4 via the circFBXL4/miR-146a-5p/STAT1 axis.
Other information
Title:

Novel roles of LSECtin in gastric cancer cell adhesion, migration, invasion, and lymphatic metastasis.

Journal: Cell Death Dis
Published: 2022/7/14
PubMed ID: 35821222