circRNA basic information
circBase ID: hsa_circ_0007312
Name: hsa_circ_SPECC1L
Synonym: circ_0007312
Host Gene: hsa-miR-764
 
 
 
Disease basic information
DO ID:
 3910
DO name: lung adenocarcinoma
Disease details: lung adenocarcinoma
Species: human
Species details: human
Sample type: tissue
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: MAPK1
Associated microRNA: hsa-miR-764
Biological function: pyroptosis and apoptosis
Molecular mechanism: miRNA sponge
Survival: poor
Supported No.:
 1
Description:

the inhibition of circ7312 decreased osimertinib resistance by promoting pyroptosis and apoptosis via the miR-764/MAPK1 axis.
Other information
Title:

Hsa_circ_0007312 Promotes Third-Generation Epidermal Growth Factor Receptor-Tyrosine Kinase Inhibitor Resistance through Pyroptosis and Apoptosis via the MiR-764/MAPK1 Axis in Lung Adenocarcinoma Cells.

Journal: J Cancer
Published: 2022/7/12
PubMed ID: 35812182