circRNA basic information
circBase ID: -
Name: hsa_circ_ME1
Synonym: CircME1
Host Gene: -
 
 
 
Disease basic information
DO ID:
 4467
DO name: clear cell renal cell carcinoma
Disease details: clear cell renal cell carcinoma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: ACHN, A498, Caki-1, 786-O, 769-P, HK2
circRNA-disease information
Detected method:
Q
S
Detected method confidence High
Expression pattern:
DS
Associated gene: -
Associated microRNA: -
Biological function: -
Molecular mechanism: -
Survival: -
Supported No.:
 1
Description:

circME1 interacted with U1 snRNP at the promoter of its parental gene ME1, thereby upregulating the expression of ME1, enhancing aerobic glycolysis of ccRCC, and promoting its malignant phenotype.
Other information
Title:

CircME1 promotes aerobic glycolysis and sunitinib resistance of clear cell renal cell carcinoma through cis-regulation of ME1.

Journal: Oncogene
Published: 2022/7/8
PubMed ID: 35798876