circRNA basic information
circBase ID: -
Name: hsa_circ_ASPH
Synonym: CircASPH
Host Gene: -
 
 
 
Disease basic information
DO ID:
 684
DO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma
Species: human
Species details: human
Sample type: tissue
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: -
Biological function: -
Molecular mechanism: miRNA sponge
Survival: poor
Supported No.:
 2
Description:

circASPH could regulate the methylation of the promoter and expression of hydrocyanic oxidase 2 (HAO2) to promote HCC progression by acting as a sponge for miR-370-3p, and miR-370-3p could target DNMT3b and increase the 5mC level.
Other information
Title:

CircASPH Promotes Hepatocellular Carcinoma Progression Through Methylation and Expression of HAO2.

Journal: Front Oncol
Published: 2022/7/8
PubMed ID: 35795047