circRNA basic information
circBase ID: hsa_circ_0006357
Name: hsa_circ_EZH2
Synonym: CircEZH2
Host Gene: hsa-miR-133b
 
 
 
Disease basic information
DO ID:
 9256
DO name: colorectal cancer
Disease details: colorectal cancer
Species: human
Species details: human
Sample type: tissue
Sample type details: -
circRNA-disease information
Detected method:
S
Detected method confidence Low
Expression pattern:
UP
Associated gene: IGF2BP2, CREB1
Associated microRNA: hsa-miR-133b
Biological function: -
Molecular mechanism: CircEZH2/hsa-miR-133b/IGF2BP2 axis, miRNA sponge
Survival: -
Supported No.:
 1
Description:

circEZH2 in modulating CRC progression, but also advocate for attenuating circEZH2/miR-133b/IGF2BP2/ CREB1 regulatory axis to combat CRC.
Other information
Title:

CircEZH2/miR-133b/IGF2BP2 aggravates colorectal cancer progression via enhancing the stability of m(6)A-modified CREB1 mRNA.

Journal: Mol Cancer
Published: 2022/7/1
PubMed ID: 35773744