circRNA basic information
circBase ID: hsa_circ_0007367
Name: hsa_circ_UBAP2
Synonym: circUBAP2
Host Gene: -
 
 
 
Disease basic information
DO ID:
 114
DO name: heart disease
Disease details: cardiogenic shock
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: NR8383
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DS
Associated gene: -
Associated microRNA: -
Biological function: migratory activity and M2 polarization
Molecular mechanism: PI3K/Akt/mTOR pathway
Survival: -
Supported No.:
 2
Description:

circUBAP2 inhibited the migratory activity and promoted M2 polarization in macrophages, declining the productions of cytokines (tumor necrosis factor [TNF]-alpha, interleukin [IL]-1beta, and monocyte chemotactic protein [MCP]-1) and the PI3K/Akt/mTOR pathway.
Other information
Title:

Circular RNA UBAP2 (hsa_circ_0007367) Correlates with Microcirculatory Perfusion and Predicts Outcomes of Cardiogenic Shock Patients Undergoing Extracorporeal Membrane Oxygenation Support.

Journal: Shock
Published: 2022/6/28
PubMed ID: 35759302