circRNA basic information
circBase ID: -
Name: hsa_circ_PTTG1IP
Synonym: circPTTG1IP
Host Gene: hsa-miR-16-5p
 
 
 
Disease basic information
DO ID:
 684
DO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma
Species: human
Species details: human
Sample type: tissue
Sample type details: -
circRNA-disease information
Detected method:
Q
S
Detected method confidence High
Expression pattern:
DN
Associated gene: RNF125/JAK1
Associated microRNA: hsa-miR-16-5p
Biological function: -
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 1
Description:

circPTTG1IP is a novel tumor suppresser circRNA in HCC and that a low circPTTG1IP level promotes HCC development via the miR-16-5p/RNF125/JAK1 axis.

Other information
Title:

Down-regulation of circPTTG1IP induces hepatocellular carcinoma development via miR-16-5p/RNF125/JAK1 axis.

Journal: Cancer Lett
Published: 2022/6/17
PubMed ID: 35710093