circRNA basic information
circBase ID: -
Name: hsa_circ_ARHGAP32
Synonym: Circ_ARHGAP32
Host Gene: hsa-miR-665
 
 
 
Disease basic information
DO ID:
 1936
DO name: atherosclerosis
Disease details: atherosclerosis
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: VSMCs
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: FGF2
Associated microRNA: hsa-miR-665
Biological function: VSMCs proliferation and migration
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 1
Description:

Circ_ARHGAP32 might be a potential target for AS treatment, which promoted ox-LDL-induced VSMCs proliferation and migration by regulating miR-665/FGF2 network.
Other information
Title:

Circ_ARHGAP32 acts as miR-665 sponge to upregulate FGF2 to promote ox-LDL induced vascular smooth muscle cells proliferation and migration.

Journal: Clin Hemorheol Microcirc
Published: 2022/6/7
PubMed ID: 35662113