circRNA basic information
circBase ID: hsa_circ_0017109
Name: hsa_circ_NID1
Synonym: circ_0017109
Host Gene: hsa-miR-135b-3p
 
 
 
Disease basic information
DO ID:
 3910
DO name: lung adenocarcinoma
Disease details: lung adenocarcinoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: H1299, A549, H460, BEAS-2B
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DS
Associated gene: -
Associated microRNA: hsa-miR-135b-3p
Biological function: cell migration, invasion, and proliferation
Molecular mechanism: -
Survival: -
Supported No.:
 1
Description:

melatonin decreases the expression of circ_0017109 and suppresses the non-small-cell lung cancer cell migration, invasion, and proliferation through decreasing TOX3 expression via direct activation of miR-135b-3p.
Other information
Title:

Melatonin may suppress lung adenocarcinoma progression via regulation of the circular noncoding RNA hsa_circ_0017109/miR-135b-3p/TOX3 axis.

Journal: J Pineal Res
Published: 2022/6/7
PubMed ID: 35661247