circRNA basic information
circBase ID: hsa_circ_0007905
Name: hsa_circ_STX6
Synonym: CircSTX6
Host Gene: hsa-miR-449b-5p
 
 
 
Disease basic information
DO ID:
 3498
DO name: pancreatic ductal adenocarcinoma
Disease details: pancreatic ductal adenocarcinoma
Species: human
Species details: human
Sample type: tissue
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-449b-5p
Biological function: proliferation and metastasis
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 1
Description:

circSTX6 facilitates proliferation and metastasis of PDAC cells by regulating the expression of MYH9 through the circSTX6/miR-449b-5p axis and circSTX6/CUL2/HIF1A signaling pathway.
Other information
Title:

CircSTX6 promotes pancreatic ductal adenocarcinoma progression by sponging miR-449b-5p and interacting with CUL2.

Journal: Mol Cancer
Published: 2022/6/2
PubMed ID: 35650603