circRNA basic information
circBase ID: hsa_circ_0000370
Name: hsa_circ_FLI1
Synonym: circ-FLI1
Host Gene: hsa-miR-197-3p
 
 
 
Disease basic information
DO ID:
 219
DO name: colon cancer
Disease details: colon cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: HCT116, SW480, SW620, LoVo
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DS
Associated gene: DKC1
Associated microRNA: hsa-miR-197-3p
Biological function: L-OHP resistance
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 1
Description:

circ-FLI1 might confer L-OHP resistance and malignant progression of CC presumably through the circ-FLI1/miR-197-3p/DKC1 ceRNA axis.
Other information
Title:

Silencing circular RNA-friend leukemia virus integration 1 restrained malignancy of CC cells and oxaliplatin resistance by disturbing dyskeratosis congenita 1.

Journal: Open Life Sci
Published: 2022/6/2
PubMed ID: 35647294