circRNA basic information
circBase ID: -
Name: hsa_circ_Nup188
Synonym: circNup188
Host Gene: hsa-miR-760-3p
 
 
 
Disease basic information
DO ID:
 2316
DO name: brain ischemia
Disease details: cerebral ischemia
Species: human
Species details: human
Sample type: cell line
Sample type details: PC12
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DS
Associated gene: NF-kappaB
Associated microRNA: hsa-miR-760-3p
Biological function: -
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 1
Description:

circNup188 might up-regulate Map3k8 expression through sponging miR-760-3p and then activate NF-kappaB pathway, which was involved in cerebral ischemia development.
Other information
Title:

circNup188/miR-760-3p/Map3k8 axis regulates inflammation in cerebral ischemia.

Journal: Mol Cell Probes
Published: 2022/6/1
PubMed ID: 35636640