circRNA basic information
circBase ID: hsa_circ_0001495
Name: hsa_circ_CCNB1
Synonym: circ_0001495
Host Gene: hsa-miR-526b-3p
 
 
 
Disease basic information
DO ID:
 4362
DO name: cervical cancer
Disease details: cervical cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: CC cell lines (Hela), 293 T cells, human cervical epithelium cells (End1/E6E7)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-526b-3p
Biological function: Hsa_circ_0001495 knockdown or TMBIM6 knockdown suppressed cell proliferation, migration, glycolysis, while promoted cell apoptosis in vitro, and hsa_circ_0001495 silence curbed tumor growth in vivo.
Molecular mechanism: hsa_circ_0001495 acted as a sponge for hsa-miR-526b-3p to regulate TMBIM6 expression
Survival: -
Supported No.:
 2
Description:

In summary, hsa_circ_0001495 regulated the progression of CC by regulating miR-526b-3p/TMBIM6/mTOR pathway.
Other information
Title:

Hsa_circ_0001495 contributes to cervical cancer progression by targeting miR-526b-3p/TMBIM6/mTOR axis.

Journal: Reprod Biol
Published: 2022/5/10
PubMed ID: 35533615