circRNA basic information
circBase ID: hsa_circ_0007707
Name: -
Synonym: circ-0007707
Host Gene: hsa-miR-429
 
 
 
Disease basic information
DO ID:
 10534
DO name: stomach cancer
Disease details: gastric cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: lyse AGS, MKN45, GES-1
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: PDGFD
Associated microRNA: hsa-miR-429
Biological function: the circ-0007707/miR-429/PDGFD pathway had a differential expression. The results demonstrated that the pathway could regulate the progression and immune microenvironment of gastric cancer by modulating the immune-gene signature, which included two immune genes (TAB1_nd_XCR4)
Molecular mechanism: -
Survival: -
Supported No.:
 2
Description:

The circ-0007707/miR-429/PDGFD pathway may play a regulatory role in the progression and prognosis of gastric cancer by interfering with the tumor microenvironment, and the PDGFD-related immune-gene signature could be considered a moderator of prognostic factor for gastric cancer and to guide immunotherapy programs.
Other information
Title:

circ-0007707/miR-429/PDGFD Pathway Regulates the Progression of Gastric Cancer by Modulating the Immune-Gene Signature.

Journal: J Oncol
Published: 2022/5/6
PubMed ID: 35509844