circRNA basic information
circBase ID: hsa_circ_0084927
Name: hsa_circ_ESRP1
Synonym: circ_0084927
Host Gene: -
 
 
 
Disease basic information
DO ID:
 9256
DO name: colorectal cancer
Disease details: colorectal cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human normal colonic epithelial cell lines (NCM460), COAD cells (HCT116, SW480, DLD1, SW620, RKO)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: -
Biological function: hsa_circ_0084927 can promote the proliferation, migration and invasion of COAD cells.
Molecular mechanism: constructed a ceRNA: network has_circ_0084927/hsa-miR-106b-5p/VEGFA. The ceRNA network indicates that hsa_circ_0084927 may affect the prognosis of COAD through the regulation of cell cycle, apoptosis and other pathways.
Survival: -
Supported No.:
 2
Description:

Our research results indicate that hsa_circ_0084927 has a cancer-promoting effect and may be used as a circulating tumor marker for COAD prognosis. In addition, this study proposes a new ceRNA network to provide new insights for the targeted therapy of COAD.
Other information
Title:

Evaluation of Diagnostic and Prognostic Value of hsa_circ_0084927 and Analysis of Associated ceRNA Network in Colorectal Cancer.

Journal: Int J Gen Med
Published: 2022/5/3
PubMed ID: 35493197