circRNA basic information
circBase ID: hsa_circ_0000977
Name: hsa_circ_NOL10
Synonym: circ_0000977
Host Gene: hsa-miR-874-3p
 
 
 
Disease basic information
DO ID:
 3748
DO name: esophagus squamous cell carcinoma
Disease details: esophageal squamous cell carcinoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: ECA109, TE12 ESCC cells
circRNA-disease information
Detected method:
Q
S
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-874-3p
Biological function: Elevated hsa_circ_0000977 promoted cell proliferation, migration and inhibited apoptosis in ESCC cells.
Molecular mechanism: hsa_circ_0000977 might function as a micro-RNA sponge to competitively bind hsa-miR-874-3p.
Survival: -
Supported No.:
 1
Description:

Disordered hsa_circ_0000977 expression can promote carcinogenesis in ESCC and might serve as a diagnostic biomarker to evaluate the occurrence and development of esophageal cancer.
Other information
Title:

Upregulation of hsa_circ_0000977 participates in esophageal squamous cancer progression by sponging miR-874-3p.

Journal: J Clin Lab Anal
Published: 2022/4/28
PubMed ID: 35476874