circRNA basic information
circBase ID: -
Name: -
Synonym: CircRNA608
Host Gene: mmu-miR-222
 
 
 
Disease basic information
DO ID:
 80547
DO name: non-alcoholic steatohepatitis
Disease details: nonalcoholic steatohepatitis
Species: mouse
Species details: mouse
Sample type: PDX
Sample type details: -
circRNA-disease information
Detected method:
Q
S
Detected method confidence High
Expression pattern:
DN
Associated gene: -
Associated microRNA: mmu-miR-222
Biological function: circ608 was significantly down-regulated in lipotoxic HSCs and in livers of NASH-related liver fibrosis mice.
Molecular mechanism: circ608/mmu-miR-222/PINK1 axis, miRNA sponge
Survival: -
Supported No.:
 1
Description:

Circ608 could promote PINK1-mediated mitophagy of HSCs though inhibiting miR222 in NASH-related liver fibrosis.
Other information
Title:

CircRNA608-microRNA222-PINK1 axis regulates the mitophagy of hepatic stellate cells in NASH related fibrosis.

Journal: Biochem Biophys Res Commun
Published: 2022/4/19
PubMed ID: 35436629