circRNA basic information
circBase ID: hsa_circ_0001823
Name: -
Synonym: circ_0001823
Host Gene: hsa-miR-613
 
 
 
Disease basic information
DO ID:
 4362
DO name: cervical cancer
Disease details: cervical cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: Hela, CaSki CC cells
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: RAB8A
Associated microRNA: hsa-miR-613
Biological function: Knockdown of circ_0001823 inhibited the malignant behavior of the CC cells
Molecular mechanism: Knockdown of circ_0001823 inhibited the malignant behaviors of the CC cells via regulating the hsa-miR-613/RAB8A axis.
Survival: -
Supported No.:
 1
Description:

The circ_0001823 and RAB8A expressions were increased, and miR-613 were decreased in the CC cells and tissues. Knockdown of circ_0001823 inhibited the malignant behavior of the CC cells, which was antagonized by miR-613 inhibitor. Over-expressed RAB8A reversed the miR-613 effects in the CC cells. Knockdown of circ_0001823 inhibited the malignant behaviors of the CC cells via regulating the miR-613/RAB8A axis.
Other information
Title:

Circular RNA 0001823 aggravates the growth and metastasis of the cervical cancer cells through modulating the microRNA-613/RAB8A axis.

Journal: Bioengineered
Published: 2022/4/19
PubMed ID: 35435110