circRNA basic information
circBase ID: hsa_circ_0081534
Name: hsa_circ_EPHB4
Synonym: circ_0081534
Host Gene: hsa-miR-874-3p
 
 
 
Disease basic information
DO ID:
 9261
DO name: nasopharynx carcinoma
Disease details: nasopharyngeal carcinoma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: human NPC cell lines (5-8F, HNE-3, 6-10B, C666-1)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-874-3p
Biological function: Knockdown of circ_0081534 repressed NPC cell proliferation, migration, invasion, EMT, and triggered NPC cell apoptosis.
Molecular mechanism: circ_0081534 regulated FMNL3 expression through serving as a hsa-miR-874-3p sponge.
Survival: -
Supported No.:
 1
Description:

circ_0081534 interference repressed NPC progression partly by modulating the miR-874-3p/FMNL3 axis.
Other information
Title:

Hsa_circ_0081534 facilitates malignant phenotypes by sequestering miR-874-3p and upregulating FMNL3 in nasopharyngeal carcinoma.

Journal: Auris Nasus Larynx
Published: 2022/4/17
PubMed ID: 35428519