circRNA basic information
circBase ID: hsa_circ_0025933
Name: hsa_circ_NELL2
Synonym: -
Host Gene: hsa-miR-127-5p
 
 
 
Disease basic information
DO ID:
3748
DO name: esophagus squamous cell carcinoma
Disease details: esophageal squamous cell carcinoma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: OE33, FLO-1
circRNA-disease information
Detected method:
Q
S
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-127-5p
Biological function: sponging miR-127-5p
Molecular mechanism: circNELL2 knockdown inhibited the proliferation of ESCC cells in vitro and in vivo
Survival: -
Supported No.:
2
Description:

circNELL2 promoted the progression of ESCC cells via sponging miR-127-5p, and it has the potential to serve as a novel prognostic and therapeutic target for ESCC.

Other information
Title:

Circular RNA circNELL2 Acts as the Sponge of miR-127-5p to Promote Esophageal Squamous Cell Carcinoma Progression.

Journal: Onco Targets Ther
Published: 2020/9/29
PubMed ID: 32982311