circRNA basic information
circBase ID: hsa_circ_0007967
Name: hsa_circ_ATF2
Synonym: circ_0007967
Host Gene: hsa-miR-411-5p
 
 
 
Disease basic information
DO ID:
 10534
DO name: stomach cancer
Disease details: gastric cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: HEK-293T, MGC803, BGC823, HGC27, SGC7901, AGS, GES1
circRNA-disease information
Detected method:
S
Detected method confidence Low
Expression pattern:
UP
Associated gene: MAML3
Associated microRNA: hsa-miR-411-5p
Biological function: sa_circ_0007967 was highly expressed in gastric cancer tissues than adjacent normal tissues. Overexpressing hsa_circ_0007967 promoted gastric cancer cell proliferation in vitro and in vivo, while suppression of hsa_circ_0007967 inhibited gastric cancer cell proliferation in vitro and in vivo.
Molecular mechanism: hsa_circ_0007967 sponged hsa-miR-411-5p to increase MAML3 expression.
Survival: -
Supported No.:
 1
Description:

hsa_circ_0007967 is a promising biomarker for gastric cancer diagnosis and a potential molecule for gastric cancer treatment.
Other information
Title:

Hsa_circ_0007967 promotes gastric cancer proliferation through the miR-411-5p/MAML3 axis.

Journal: Cell Death Discov
Published: 2022/4/1
PubMed ID: 35354791