circRNA basic information
circBase ID: -
Name: hsa_circ_Atp9b
Synonym: circAtp9b
Host Gene: hsa-miR-17-92a
 
 
 
Disease basic information
DO ID:
 11476
DO name: osteoporosis
Disease details: osteoporosis
Species: human
Species details: human
Sample type: tissue
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-17-92a
Biological function: CircAtp9b was detected in both nucleus and cytoplasm, and it directly interacted with premature miR-17-92a.
Molecular mechanism: circAtp9b suppressed the maturation of miR-17-92a.
Survival: -
Supported No.:
 1
Description:

CircAtp9b is LPS-inducible and upregulation of circAtp9b in OS promotes the apoptosis of osteoblasts by reducing the formation of mature miR-17-92a.
Other information
Title:

LPS-inducible circAtp9b is highly expressed in osteoporosis and promotes the apoptosis of osteoblasts by reducing the formation of mature miR-17-92a.

Journal: J Orthop Surg Res
Published: 2022/3/30
PubMed ID: 35346278