circRNA basic information
circBase ID: hsa_circ_0085154
Name: hsa_circ_PABPC1
Synonym: -
Host Gene: -
 
 
 
Disease basic information
DO ID:
 684
DO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: MHCC-97h, LM3, LO2, SK-Hep1, HepG2, Huh7
circRNA-disease information
Detected method:
M
Detected method confidence Low
Expression pattern:
DN
Associated gene: -
Associated microRNA: -
Biological function: inhibit HCC tumor growth
Molecular mechanism: -
Survival: better
Supported No.:
 2
Description:

we found CircARSP91 (hsa_circ_0085154), one of the circRNAs downregulated by AR in an ADAR1-dependent manner, could inhibit HCC tumor growth both in vitro and in vivo.

Other information
Title:

Circular RNA expression is suppressed by androgen receptor (AR)-regulated adenosine deaminase that acts on RNA (ADAR1) in human hepatocellular carcinoma.

Journal: Cell Death Dis
Published: 2017/11/17
PubMed ID: 29144509