circRNA basic information
circBase ID: hsa_circ_0011946
Name: hsa_circ_SCMH1
Synonym: hsa_circ_0011946
Host Gene: hsa-miR-1205
 
 
 
Disease basic information
DO ID:
 4866
DO name: salivary gland adenoid cystic carcinoma
Disease details: salivary adenoid cystic carcinoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: SACC cell line (SACC-LM)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-1205
Biological function: The results of the present study revealed that the expression levels of hsa_circ_0011946 were significantly upregulated in cancer tissues from patients with SACC. The knockdown of hsa_circ_0011946 expression inhibited the proliferation, invasion and migration of SACC cells, thereby inhibiting the EMT process
Molecular mechanism: hsa_circ_0011946 expression inhibited the proliferation, invasion and migration of SACC cells, thereby inhibiting the EMT process, which was achieved by downregulating hsa-miR-1205 expression. I
Survival: -
Supported No.:
 1
Description:

circRNA hsa_circ_0011946 was discovered to promote the malignant process of SACC by downregulating miR-1205 expression.
Other information
Title:

Circular RNA hsa_circ_0011946 promotes the malignant process of salivary adenoid cystic carcinoma by downregulating miR-1205 expression.

Journal: Exp Ther Med
Published: 2022/3/24
PubMed ID: 35317442