circRNA basic information
circBase ID: hsa_circ_0018289
Name: hsa_circ_SYT15
Synonym: hsa_circ_0018289
Host Gene: hsa-miR-1294
 
 
 
Disease basic information
DO ID:
 4362
DO name: cervical cancer
Disease details: cervical cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: CC cells HeLa£¬SiHa
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: ICMT
Associated microRNA: hsa-miR-1294
Biological function: Hsa_circ_0018289 was elevated in CC tissues and cells, its deficiency could repress growth, metastasis, and glycolysis of CC cells in vitro, as well as hamper tumor growth in vivo.
Molecular mechanism: Hsa_circ_0018289 sponged hsa-miR-1294 while hsa-miR-1294 bound with ICMT, and the inhibition of hsa-miR-1294 or addition of ICMT could partially relieve the effect caused by hsa_circ_0018289 depletion.
Survival: -
Supported No.:
 3
Description:

Hsa_circ_0018289 contributes to malignant development by regulating the miR-1294/ICMT axis, affording novel insight into CC therapy.
Other information
Title:

CircRNA hsa_circ_0018289 exerts an oncogenic role in cervical cancer progression through miR-1294/ICMT axis.

Journal: J Clin Lab Anal
Published: 2022/3/22
PubMed ID: 35312113