circRNA basic information
circBase ID: -
Name: hsa_circ_FOXM1
Synonym: CircFOXM1
Host Gene: hsa-miR-136-5p
 
 
 
Disease basic information
DO ID:
 9261
DO name: nasopharynx carcinoma
Disease details: nasopharyngeal carcinoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human NPC cell lines (SUNE1, CNE1, HNE1, CNE2, 5_8F, 6_10B, C666), a human normal nasopharyngeal epithelial cell line (NP69)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-136-5p
Biological function: Knockdown of CircFOXM1 inhibited the proliferation and invasion of nasopharyngeal carcinoma cells.
Molecular mechanism: CircFOXM1 promotes the malignant proliferation of nasopharyngeal carcinoma cells by regulating the hsa-miR-136-5p-SMAD2 axis
Survival: poor
Supported No.:
 1
Description:

CircFOXM1 promotes the malignant proliferation of nasopharyngeal carcinoma cells by regulating the miR-136-5p-SMAD2 axis.
Other information
Title:

CircFOXM1 acts as a ceRNA to upregulate SMAD2 and promote the progression of nasopharyngeal carcinoma.

Journal: Mol Genet Genomic Med
Published: 2022/3/11
PubMed ID: 35266323