circRNA basic information
circBase ID: hsa_circ_0085494
Name: hsa_circ_TMEM65
Synonym: circ_0085494
Host Gene: hsa-miR-497-5p
 
 
 
Disease basic information
DO ID:
 10283
DO name: prostate cancer
Disease details: prostate cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human prostate epithelial cell (RWPE-1), PCa cell lines (PC3, DU145, 22RV1, VCaP)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: NRBP1
Associated microRNA: hsa-miR-497-5p
Biological function: circ_0085494 absence suppressed PCa cell proliferation, migration, and invasion
Molecular mechanism: circ_0085494/hsa-miR-497-5p/NRBP1 axis, miRNA sponge
Survival: -
Supported No.:
 1
Description:

Our finding revealed that circ_0085494 downregulation might repress PCa tumor progression through in part regulating the miR-497-5p/NRBP1 pathway.
Other information
Title:

The Circular RNA Circ_0085494 Regulates Prostate Cancer Progression Through NRBP1/miR-497-5p Axis.

Journal: Biochem Genet
Published: 2023/2/16
PubMed ID: 36790665